Infertility & Sexual Dysfunction(구연) Oral Session 2 / Infertility & Sexual Dysfunction (O-011) Crystal A (3F) 11월28일(수) 13:00-14:00 Comparative analysis of corpoplasty with buccal mucosa graft and tunica vaginalis in Peyronie's disease. Department of urology and andrology, Astana Medical University, First Astana City Hospital. Kazakhstan Keulimzhayev.Nurbol, Ainayev Ernur, Zhanbyrbekuly Ulanbek Objective: Extensive evaluation of long-term results and patient satisfaction was performed after application of buccal mucosa graft and tunica vaginalis for replacement of fibrotically affected tunica albuginea of the penis during progressive course of Peyronie's disease. Materials and methods: The investigation involves analysis of results of corporoplasty performed on 17 patients. As an autograft, tunica vaginalis was used for 10 (58.8%) patients and 7 (41.2%) patients were given buccal mucosa graft. The average age of patients was 44.25+-11.88 years. All patients underwent surgery promptly, there were no intraoperative complications. The nearest postoperative period proceeded smoothly. The results were evaluated in a period of 3 months, 6 months and 12 months later. Results: As a result, a comparative analysis of the obtained results and the use of different types of autologous materials for corporoplasty revealed the advantage of the buccal graft. In terms of the parameters, the angles of curvature of the penis after 12 months of observation were 12.7 ± 6.11° and 7.43 ± 3.82° for 1A and 1B subgroups respectively (p-value < 0.040). As regards the parameters of the erectile function of patients according to the IIEF-5 questionnaire, 12 months of follow-up conducted after the operation resulted in 20.4 ± 2.82 and 22.2 ± 2.44 for groups 1A and 1B subgroups respectively (p > 0.352). Reduction of the average ICEF score in 1A subgroup can be associated with the rejection of combined surgical intervention. When comparing the duration of an operation, a statistically significant difference was obtained, which are 211.0 ± 15.2 for 1A subgroup and 194.4 ± 18.1 for subgroup 1B with p-value<0.05. Conclusion: Overall, a comparative analysis and discussion of the performed corporoplasty using the tunica vaginalis and buccal mucosa graft showed the slight advantage of the buccal mucosa graft with prolonged surgical intervention. With the use of the tunica vaginalis and buccal mucosa graft, a significant reduction in the angle of curvature was achieved, and the erectile status of the patients was improved, which remained stable in the long-term period 12 months later. keywords : Peyronie's disease; buccal graft; vaginal tunic; clinical results