Cancer - Kidney(구연) Oral Session 5 / Cancer - Kidney (Ⅰ) (O-044) Grand Ballroom(2F) 11월28일(수) 14:00-15:00 로봇 보조 부분 신절제술은 신기능 초기 회복과 관련 있다: 신장스캔을 이용한 개복, 복강경, 로봇 부분 신절제술의 비교 울산대학교 의과대학 비뇨기과학교실 최세영, 임범진, 한재현, 경윤수, 안동현, 김휘우, 이원철, 채한규, 이재훈, 최원석, 유달산, 정인갑, 송채린, 홍범식, 홍준혁, 안한종, 김청수 Purpose: We compared the functional outcomes of open, laparoscopic, and robot-assisted partial nephrectomy (OPN, LPN, and RAPN). Materials and Methods: We identified 610 patients who underwent partial nephrectomy for renal cell carcinoma (285 OPN, 96 LPN, and 229 RAPN). All patients had preoperative diethylene triamine penta-acetic acid (DTPA) and postoperative DTPA within 1 year. We excluded patients with multiple renal masses and patients who received immunotherapy or chemotherapy. Disease-free survival was estimated using the Kaplan-Meier method. Predictive factors for glomerular filtration rate (GFR) reduction were assessed using multivariate linear regression. Results: Postoperative complications were similar in the 3 groups. There was no significant difference in disease-free survival among the groups (p=0.080). Within 1 postoperative year, OPN showed a significantly lower mean ipsilateral GFR than LPN and RAPN (28.9 vs 32.4 vs 32.7 mL/minute/1.73 m2, respectively; p<0.001). On multivariate analysis within 1 year, tumor size (beta=1.07, p=0.001), R.E.N.A.L. N nephrometry score (beta=1.35, p=0.004), preoperative GFR (beta=0.19, p=0.001), ischemic time (beta=0.15, p=0.001), and operation type (OPN vs RAPN: beta=2.82, p=0.001) were significantly associated with GFR reduction. At 2–4 years, tumor size (beta=1.91, p<0.001), R.E.N.A.L. L score (beta=1.53, p=0.033), preoperative GFR (beta=0.19, p<0.001), cold ischemia (beta=−3.63, p=0.002), and operation type (LPN vs RAPN: beta=5.36, p=0.005) were significantly associated with GFR reduction. Conclusions: There was no difference in postoperative complications and disease-free survival among operation types. RAPN could help to promote earlier recovery of ipsilateral GFR than OPN and may have better late recovery of ipsilateral GFR than LPN. keywords : robot-assisted; glomerular filtration rate; recovery of function