Cancer - Prostate(구연) (NP-030) 70세 이상의 환자군에서 근치적전립선적출술의 경향과 요자제 회복의 예측인자: 70세 이하 환자군과 12년에 걸친 비교연구 1서울대학교 의과대학 분당서울대학교병원 비뇨의학과, 2가톨릭관동대학교 국제성모병원 비뇨의학과 이영주¹, 정진우², 김정준¹, 이학민¹, 오종진¹, 이상철¹, 홍성규¹, 변석수¹, 이상은¹, 정성진¹ Objectives: While advances in surgical techniques and modalities seem to facilitate recovery of urinary continence (UC) after radical prostatectomy (RP), old age is still considered a risk factor for delay or failure to achieve UC and many older men with a significant disease often hesitate to receive RP due to the risk of such complications. We evaluated the contemporary trends of RP in the elderly aged >70 years and compared its predictors for the recovery of UC with those for patients aged ≤70 years over time. Materials and Methods: A retrospective cohort of 2,301 patients with eligible criteria was reviewed. Patients were divided into two groups based on age at surgery (>70 vs ≤70) and four groups by the surgery year (2004-2006, 2007-2009, 2010-2012, and 2013-2015). Clinicosurgical characteristics and the recovery rates and predictors of UC were compared between both age groups over the study period. Multivariable logistic regression analyses were performed and the effects of each predictor on the recovery of UC at 12 months were compared between both age groups. Results: The proportion of patients aged >70 years gradually increased up to 30.0% in 2013-2015, and the rate of robot-assisted RP and neurovascular bundle (NVB) saving continued to rise up to 80.0% and 67.4% in 2013-2015 in older patients. Although overall recovery rate of UC within 12 months (3 months) in patients aged >70 years was lower than that in those aged ≤70 years (81.5% (52.6%) vs 88.6% (60.9%); P <0.001, respectively), the gap of recovery rate within 12 months had been narrowed between both age groups since the second quarter of the study period (Fig. 1). Among younger patients, age, robot-assisted RP, prostate volume, membranous urethral length (MUL), and NVB saving were founded to be the predictors for the recovery of UC within 3 or 12 months. In contrast, only age and MUL were revealed to be the predictors for the recovery within 3 and 12 months in patients aged >70 years. Conclusions: Based on our contemporary RP series, the proportion of patients aged >70 years gradually increased over 12 years, and the use of robot-assisted RP and NVB saving has been expanded in this population. Unlike younger patients, only age and MUL, possibly associated with the inherent function of the urinary sphincter, were the predictors for the recovery of UC in patients aged >70 years. keywords : Elderly, Radical prostatectomy, Urinary incontinence