Endourology & Stone Disease(구연) (NP-044)

요관결석 환자에서 요관점막의 염증성 변화 분류와 이에 영향을 미치는 인자
양산부산대학교병원, 부산대학교 의과대학 비뇨의학과교실
이승수, 남종길, 한지연, 정문기, 정재민, 박성우, 이상돈
Purpose : In ureterolithotripsy, we often find ureteral mucosa edema or fibroepithelial polyps with impacted ureter stones. We suggest new grading system of inflammatory change of ureteral mucosa in ureter stone disease, and analyze associated factors.
Materials and Methods : 153 stones of 142 patients, who underwent ureterolithotripsy between April 2015 and March 2018 by a single surgeon, were reviewed. Patients who underwent extracorporeal shock wave lithotripsy for the same stone before surgery were excluded. From the ureteroscopic image, status of ureteral mucosa where the stone locate is classified into four grades. “Grade 0” is defined as normal mucosa, “Grade 1” indicates small change and edema of mucosa and stone is not impacted. “Grade 2” indicates moderate edema of mucosa or some fibroepithelial polyps and stone is mild impacted. “Grade 3” indicates severe edema of mucosa or highly developed fibroepithelial polyps and severely impacted stone. We evaluated patients’ sex and age, stone size and location, hydronephrosis grade (Society of Fetal Ultrasound (SFU) grade) in each grade.
Results : The number of patients were 26 in grade 0, 51 in grade 1, 44 in grade 2, and 22 in grade 3. The mean ages were 60.7, 61.6, 57.9, and 49.7 years old, respectively. The mean size of stone were 8.4, 10.0, 9.5, and 12.0 mm, respectively. In all grades, the most common stone location is upper ureter. Analyzing hydronephrosis, in grade 0, SFU grade 2 was the most and 3 was the second. In grade 1, SFU grade 3 was the most and 2 was the second. In grade 2 and 3, SFU grade 4 was the most and 3 was the second (Table 1). The SFU grade of hydronephrosis was the only associated factor with inflammatory change of ureteral mucosa in ureter stone.
Conclusions : In conclusions, severe hydronephrosis in preoperative computed tomography or ultasonography image would favor severe inflammatory change of ureteral mucosa and impacted ureter stone.
keywords : Ureter stone, Ureteral mucosa, Hydronephrosis

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