Endourology & Stone Disease(구연) MP Session Ⅱ (MP-015) Geumkang Hall (Avenue 2F) 11월 28일(수) 17:00-18:00 Significance of albumin to globulin ratio as a predictor of febrile urinary tract infection after ureteroscopic lithotripsy and retrograde intrarenal surgery 경북대학교 의과대학 비뇨의학과학교실 이승윤,민경찬,김상원,정재욱,하윤석,최석환,이준녕,김현태,김태환,유은상,권태균,정성광,김범수 Purpose: Albumin and globulin are main components of serum protein, and these proteins act a pivotal role in acute inflammatory reactions as well as in chronic inflammation. Many studies showed that albumin to globulin ratio (AGR) had been used as a prognostic biomarker for cancer prognosis. However, limited studies were done so far whether AGR could be used as an innovative biomarker to predict infectious condition after operative management. Therefore, we aimed to analyze effectiveness of AGR in predicting postoperative urinary tact infection (UTI) after ureteroscopic lithotripsy (URS) and retrograde intrarenal surgery(RIRS). Materials and Methods: From January 2013 to May 2018, 332 patients underwent URS. including retrograde intrarenal surgery (RIRS). The rate of postoperative febrile UTI and the risk factors for postoperative febrile UTI were analyzed using logistic regression analysis. The patients were divided into post-opeartive UTI group and non-post operative UTI group, and AGR with other demographic and peri-operative data were compared to predict the development of febrile UTI. Results: Of 332 patients, postoperative febrile UTI occurred in 41 (12.3%) patients. Univariate analysis showed that presence of diabetes mellitus, stone size and AGR was significant factor to predict febrile UTI after URS. In the multivariate logistic analysis, AGR and stone size were independently correlated with postoperative febrile UTI (p=0.001 and p=0.012, respectively). Receiver operating curve analysis showed that the cut-off value of the AGR that could predict a high risk of keywords : Ureteroscopy, Urinary tract infection, Albumin to globulin ratio