Cancer - Prostate(구연) MP Session Ⅰ (MP-003) Geumkang Hall (Avenue 2F) 11월 28일(수) 16:00-17:00 초음파-MRI 융합 전립선 표적 생검 코어의 최적 수에 대한 분석 부산대학교 의과대학 비뇨기과학 교실 김경환, 백승룡, 박지훈, 강병진, 박시균, 구자윤, 하홍구 Objective: To evaluate the optimal number of ultrasound-MRI fusion target biopsy cores Materials and Methods: We identified 151 patients who underwent concurrent ultrasound guided systemic prostate biopsy and ultrasound-MRI fusion target biopsy from October, 2016 through July, 2018 at department of urology of PNUH. All patients underwent mpMRI before biopsy. Promising targets based on PI-RADS scores were subject to target biopsy. PCa detection rates were compared in systemic vs. target biopsies and target vs. target biopsies with different core numbers. Results: Mean of age, PSA level and prostate volume showed no significant differences in systemic vs. target biopsy and target vs. target biopsy with different core numbers. Biopsy cores and positive biopsy cores were lower in target biopsy than systemic biopsy (4.0 vs 12.0; p < 0.001, 1.0 vs 1.8; p = 0.026, respectively). Positive biopsy core rate were higher in target biopsy (23.5 %) than systemic biopsy (14.9 %), but there was no significant differences (p = 0.666). PCa detection rate was lower in 2 cores target biopsy (20.9 %) than in systemic biopsy (43.7 %, p = 0.007). 4, 6 and 8 cores target biopsies had similar PCa detection rates with systemic biopsy. 6 cores target biopsy showed the highest PCa and csPCA detection rate (45.8 %, 37.5 %, respectively), but there was no significant differences compared with systemic biopsy (p = 0.846, 0.819, respectively). Conclusion: 6 cores target biopsy showed the highest PCa and csPCA detection rates. 6 can be the optimal number of cores in ultrasound-MRI fusion target biopsy. keywords : optimal cores, target biopsy, prostate cancer