Cancer - Kidney(구연) Oral Session 5 / Cancer - Kidney (Ⅰ) (O-045) Grand Ballroom(2F) 11월28일(수) 14:00-15:00 RENAL nephrometry 점수 8점 이상의 복잡도가 높은 신장암에서 로봇 보조 신장 부분 절제술과 개복 부분 절제술의 비교 분당서울대학교병원 김정준, 오종진, 이상철, 홍성규, 이상은, 변석수 Introduction: To evaluate and compare the outcomes of robot-assisted partial nephrectomy (RAPN) in highly complex tumors with open partial nephrectomy (OPN) in single-institutional series of RAPN, as limited data are available about the efficacy and safety of RAPN in highly complex renal tumors. Methods: We evaluated 708 patients who received RAPN or OPN for either highly complex renal tumors from 2004 to 2015 and included in the single-institutional, retrospective database. Highly complex renal tumors were defined as the RENAL nephrometry score ≥8. Results: Of cases, the 372 patient underwent RAPN and 336 patients underwent OPN for the treatment of the highly complex tumor. There was no difference between the groups in terms of the comorbidity scores (ECOG, ASA), the size, laterality and preoperative clinical stage and RENAL nephrometry score. The age was slightly younger among RAPN group. In terms of surgical outcome, RAPN demonstrated shorter operation time and smaller estimated blood loss. The rate of radical conversion was not different. The pathologic characteristics, the rate of positive margin was also not different between two surgical approaches. However, the length of safety margin was longer among OPN. The complication rate classified by Clavien-Dindo and 1-year renal function outcome in terms of estimated glomerular filteration rate were also not different between groups. After 1:1 propensity-matching of clinically confounding variables, the most of efficacy and safety profiles were comparable. Conclusions: RAPN demonstrated comparable surgical outcome with OPN, the classic gold-standard surgical method for the treatment of highly complex renal tumors in terms of efficacy and safety profile keywords : Robot-assisted laparoscopic partial nephrectomy, Open partial nephrectomy, comparison