Cancer - Prostate(구연) International Session I (I-02)
Rm. 202
10월 31일(목) 15:00-16:00
Would MP-MRI exclude patients from Active surveillance when they are eligible?
(1)department of urology , imam abdulrahman bin faisal university Saudi arabia , currently fellow in severence hospital department of urology , yonsei university
(2) Department of urology Yonsei University
HATEM ALTHUBIANY(1),Koon ho Rha(2),Seung Hwan Lee(2)
Purpose: we have analyzed the data of post-operative pathology finding and compare it to pre-operative clinical and MRI finding in low risk patients according to PRIAS protocol.
Material and Methods: We retrospectively reviewed patients who underwent Robotic assisted radical prostatectomy from 2013-2018 ,found 42 low risk candidates .we divided them into two groups , group 1 are patients who still considered low risk after final pathology, group 2 who had risk upgrade by being higher stage or gleason score. We compared both groups by pre-op PSA, PSA density ,age, prostate size in TRUS and MRI and the association between MRI finding and final pathology outcome
Result: Group 1 (G1) who have no risk upgrade in the final pathology (n=14, 33.3%) and Group2 (G2) who have risk upgrade in the final pathology (n=28 , 66.7%). Mean age were different between both groups G1 : 62.2(8.4) vs G2:67.2(6.93) P=0.05 , other variables showed no significant differences between the two groups .However, MRI finding for clinically localized disease or extra prostatic extension was significantly correlated with the final pathology finding in low risk patients detecting 12 out of 17(70.6%) patient with extra capsular extension in the final pathology that was not detected clinically by DRE.
Conclusion: performing MRI before enrolling low risk patients in active surveillance could detect a significant number of higher risk patients that could not be detected by regular means of risk stratification criteria, and that would be of a great impact on the decision making for prostate cancer treatment.
keywords : Prostate cancer, Low risk, Active surveillance,MPMRI

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