Cancer - Prostate(구연) (NP-035)

Urethral realignment with maximal urethral length and bladder neck preservation in robot-assisted radical prostatectomy: urinary continence recovery
연세대학교 의과대학 비뇨의학과교실
허지은, 고종철, 김동균, 전진형, 김진우, 이종수, 고혁준, 장원식, 최영득
Purpose: To evaluate early recovery of urinary continence after robot-assisted radical prostatectomy (RARP) with urethral realignment using bladder neck preservation (BNP) and maximal urethral length preservation (MULP)
Materials and Methods: Patients who underwent RARP between 2014 and 2017 because of prostate cancer with Gleason score ≤7(3+4), ≤cT2c stage, and prostate-specific antigen level <20 ng/ml were investigated. 282 patients underwent the operation using standard method between 2014 and 2015 (group 1). 305 patients without tumors located on the anterior side, bladder neck, transitional zone, or apex on magnetic resonance imaging underwent the operation using urethral realignment between 2016 and 2017 (group 2). Continence was defined as wearing no pad or one security pad.
Results: Continence rates immediately after Foley catheter removal, at 2 weeks, and at 1, 3, 6, and 12 months after operation of group 2 were 46.9%, 63.0%, 73.4%, 90.1%, 94.8%, and 98.7%, respectively. Continence rate at 1 month of group 2 was significantly higher than that of group 1 (64.9% versus 73.4%, p=0.025). In multivariate regression analysis, age and surgical method were involved in factors of early continence recovery. Positive surgical margin rates were 21.3% and 14.8% in groups 1 and 2, respectively (p=0.039). Biochemical recurrence occurred in 16.4% in group 1 and 8.2% in groups 2 (p=0.003).
Conclusions: Urethral realignment method using BNP and MULP led to rapid continence recovery and good oncological results after RARP in young patients with GS ≤7 and organ-confined disease.
keywords : Prostate cancer, Robot-assisted radical prostatectomy, Urinary continence

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