LUTS/BPH(구연) Oral Session4 / LUTS (Ⅰ) (O-044)
Rm.203
10월 30일(수) 14:00-15:00
하부요로증상이 있는 환자에서 수술 후 전립선 요도각과 증상 호전과의 상관관계에 있어서 전립선 크기의 중요성
한림대학교 의과대학 비뇨의학과교실
심명선, 방우진, 오철영, 이용성, 조진선
Purpose: Recent studies reported the correlation of prostatic urethral angle (PUA) or intravesical prostatic protrusion (IPP) with lower urinary tract symptoms (LUTS). We investigated the effect of prostate morphology on the changes of LUTS and uroflowmetry after surgery.
Patients and Methods: The medical records of 448 patients who underwent transurethral resection of prostate (TURP) from January 2006 to December 2018 were retrospectively analyzed. Changes International Prostate Symptom Score (IPSS), maximum flow rate (Qmax), and post-void residual urine volume (PVR) 3 months after TURP were assessed. The prostatic morphologic variables including prostate volume, IPP, and PUA were measured using transrectal ultrasonography and its impact on changes of LUTS after TURP was analyzed by multivariable linear regression analysis.
Results: In patients with prostate volume <50mL, preoperative IPSS total score (IPSS-t), voiding symptom score (IPSS-vs), and storage symptom score (IPSS-ss) were significantly better in men with smaller PUA(< 41°mL) than those with larger PUA (≥ 41°) (p = 0.001, <0.001, and 0.020, respectively). Changes in IPSS-t, IPSS-vs, IPSS-ss, and PVR 3 months after TURP were significantly correlated with PUA (p < 0.001, < 0.001, 0.048, and 0.012, respectively). In multivariable analysis, PUA was independently associated with changes in IPPS-t, and IPSS-vs (p = 0.025, and < 0.001, respectively) only in patients with prostate volume <50mL, while it was not in patients with prostate volume ≥ 50mL.
Conclusion: Our result showed that PUA was significantly associated with changes of LUTS after surgery only in patients with small prostate, whereas PUA did not have clinical significance in patients with a large prostate. Therefore, in patients with small prostate and large PUA, surgery should be actively considered.
keywords : Benign prostatic hyperplasia, Lower urinary tract symptom, Prostate

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