Basic Research - Neurourology & LUTS/BPH & Others(구연) Oral Session6 / Basic Research - non-Cancer (I): Neurourology (O-064) Rm.203 10월 30일(수) 15:00-16:00 나트륨 섭취와 하부 요로 증상간의 관계 : 저나트륨 섭취가 하부요로 증상에 미치는 영향 1을지대학교 의료경영학과 2고려대학교 예방의학과 3순천향대학교 서울병원 비뇨의학과 4가톨릭대학교 인문사회의학과 노진원¹, 김경범², 박재준³, 이현영³, 김도경³, 두승환³, 양원재³, 송윤섭³, 권영대⁴, 김재헌³ Introduction: Sodium intake is known to be related with hypertension (HTN), which could impact lower urinary tracts symptoms (LUTS) indirectly. To date, only limited clinical evidences exist upon the association between sodium intake and LUTS. This cross-sectional study analyzed the association between sodium intake and the severity of LUTS in men. Methods: A cross-sectional analysis has been performed and a total of 86637 participants among total registered population of 229226 in Korean Community Health Survey (KCHS) were included for final analysis. The adjusted odds ratio (OR) or coefficient with 95% confidence interval (CI) estimates were described to show the association between sodium intake and LUTS using negative binomial regression (for the IPSS total, IPSS voiding, and IPSS storage symptoms), ordinal logistic regression (for the IPSS grade), and binomial logistic regression (for the IPSS nocturia symptoms). Results: Preference of salty taste group (high sodium intake) were significantly associated with higher IPSS total score (Coef=0.31; 95% CI=0.27, 0.35), increased risk of severe IPSS grade (OR=1.46; 95% CI=1.35, 1.57), higher IPSS voiding score (Coef=0.38; 95% CI=0.32, 0.44), higher IPSS storage score (Coef=0.25; 95% CI=0.22, 0.29), and increased risk of having IPSS nocturia symptoms (OR=1.21; 95% CI=1.16, 1.27) compared to subjects with neutral group (normal sodium intake). Prediction of IPSS score according to salty taste preference showed u shaped distribution. The observational design is a limitation Conclusions: Sodium preference for taste were significantly associated with LUTS including voiding symptom, storage symptom and nocturia. Both higher and lower intake of sodium could be unfavorable factor for severity of LUTS. keywords : lower urinary tracts symptoms (LUTS) , Sodium intake, cross-sectional study