Cancer - Bladder, Pelvis, Ureter & Others(구연) (NP-023)

상부요로상피암에서 신요관절제술 후 추적관찰 5년 이후에 방광내 재발이 일어난 환자군 분석
성균관의대 삼성서울병원
최중원, 강민용, 전황균, 정병창, 서성일, 전성수, 이현무, 성현환
Purpose
After patients who underwent nephroureterectomy for the treatment of upper tract urothelial cancer (UTUC), the cystoscopic follow-up is usually up to five years after surgery. But there is currently no clear consensus for how long it should be maintained. In this study, we try to investigate the patient characteristics and risk factors for recurrent after 5 years.

Materials & Methods
From September 1994 to May 2014, 1095 patients underwent the nephroureterectomy for the treatment of UTUC. Of them, 253 patients were included in the analysis who did not have UTUC or intravesical recurrence until five years after nephroureterectomy. By comparing the preoperative, intraoperative and pathological findings in these patients, we try to demonstrate the risk factors for intravesical recurrence after more than five years.

Results
Out of 253 patients, 7 patients recurred after 5 years (2.8%). The baseline demographics of the patients were comparable. All of the intravesical recurrence occurred was below T1 stage and was treated with TUR-B (Table. 1).
Various factors were compared which was candidate for intravesical recurrence after five years (Fig. 1). Even if there was no statistical difference, all patients who had intravesical recurrence after five years were male gender. Also, it was all ex- or current-smokers who recur more than a decade later.

Conclusion
Intravesical recurrence was rare (2.8%) after 5 years from nephroureterectomy. But for men who are ex- or current-smokers, it is recommended that follow up more than five years, and perhaps more than a decade.
keywords : UTUC, intravesical recurrence, cystoscopy

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