Cancer - Prostate(구연) (NP-039) 근치적 전립선 적출술 후 요자제의 즉시 (1주내) 혹은 매우 빠른 (1개월내) 회복; 요자제 결과와 이를 예측하는 모델 가톨릭대학교 인천성모병원 비뇨기과학교실, 분당서울대학교병원 비뇨기과학교실1 김정준, 이상철1, 정성진1, 홍성규1, 이상은1, 변석수1 PURPOSE According to the technical advances of radical prostatectomy (RP), about half of the patients recover his continence within 1 month after surgery. And some of the patients even recover immediately after the catheter removal. Hence, we conducted a study to identify the factors predict immediate (<1 week) or very early (<1 month) continence recovery. MATERIAL AND METHODS The prospectively collected whole radical prostatectomy cohort of single tertiary center (SNUBH) from Nov 2003 to May 2019 was analyzed. The definition of continence recovery was pad-free or one safety pad. The continent outcome was evaluated according to the self-administered EPIC questionnaire. The immediate recovery of continence was evaluated according to the patients’ comments recorded at out-patients chart at his first post-operative visit. The continence prognosis was analyzed by Kaplan-Meier analysis. The factor predicting immediate or very early continence recovery was analyzed by a multivariate cox proportional hazard model. The AUC of ROC of these prediction models were calculated. P<0.05 was considered as statistically significant. RESULTS A total of 4115 RPs (1004 open- and 3111 robot-assisted-) were included for the analysis. The median age was years and the median follow-up period was months. The immediately recovered and very early recovered patients were 24.5% (n=1010) and 56.8% (n=2339), respectively. The factors predict immediate recovery was young age, robotic approach, long MUL from the multivariate regression model. The surgical technique including reconstruction and nerve sparing was not related to the immediate recovery. The factors predict early recovery was young age, robotic approach, long MUL, and nerve sparing. The AUC of ROC to predict continence recovery was 0.701 (0.681-0.720, within 1 week) and 0.782 (0.743-0.821, within 1 month), respectively. CONCLUSIONS The immediate or very early recovery could be the expectable outcome after RPs in selected cases. The young age, robotic surgery, and long MUL is the strongest factor to predict these outcomes. The reconstruction and nerve-sparing technique did not influence immediate recovery. More efforts will be required not only to calibrate the prediction model but also understand the physiology of the immediate or very early recovery. keywords : Radical prostatectomy, continence, recovery