Cancer - Prostate(구연) (E-117)
Gleason score upgrading according to the numbers of target biopsy cores.
Urology, Samsung Medical Center, Urology, Samsung Medical Center, Urology, Samsung Medical Center, Urology, Samsung Medical Center, Urology, Samsung Medical Center, Urology, Samsung Medical Center, Urology, Samsung Medical Center, Urology, Samsung Medical Center, Urology, Samsung Medical Center, Radiology, Samsung Medical Center
Jae Hoon Chung, Wan Song, Minyong Kang, Hyun Hwan Song, Hwang Gyun Jeon, Byong Chang Jeong, Seong IL Seo, Seong Soo Jeon, Hyun Moo Lee, Byung Kwan Park
Background: Recently, with increase in pre-biopsy MRI, target biopsy is widely used for detection of the prostate cancer (PCa). Transrectal ultrasonography (TRUS) biopsy is very important not only for the diagnosis of PCa but also for the direction of treatment.However, in some cases, the gleason score (GS) is upgraded compared to the biopsy after radical prostatectomy (RP). We evaluated the numbers of target biopsy cores affecting GS upgrading. / Objectives: We retrospectively analyzed 404 patients who received RP from May 2017 to April 2020 who had undergone target biopsy before surgery. The baseline characteristics of patients and the pathological outcomes of TRUS biopsy and RP specimens were compared. / Materials and Methods: GS upgrade was confirmed in 145 out of 404 patients. There was a significant difference between the GS upgrade group and the non-upgrade group in the PIRAD score, clinical T stage, and number of target biopsy cores before surgery (Table 1). GS upgrade occurred in 40.70% when the number of target biopsy cores was 4 or less, and GS upgrade was confirmed in 27.40% when it was 5 or more. There were no differences in pathologic outcomes of RP specimens as a result of propsensity score matching by dividing the target biopsy cores into groups of less than 5, 5 or more into 2 groups, but there was a significant difference in the ratio of GS and GS upgrade of TRUS biopsy (Table 2). / Results and Conclusion: In this study, it was confirmed that the rate of GS upgrade was significantly lower in the number of target biopsy cores was 5 or more group compared to the case with number of target biopsy cores less than 5.
keywords : :Prostatic Neoplasms, Biopsy, Multiparametric Magnetic Resonance Imaging

프린트