Incontinence & Female Urology & Neurourology(구연) (E-184) 다양한 신경학적 질환을 가진 여성환자에서 중부요도슬링 후 과민성방광 증상의 변화 울산대학교 서울아산병원 비뇨의학과¹,신경과² 신정현¹, 박민욱¹, 박계원², 박주현¹, 주명수¹ Aims We investigated surgical outcomes and changes of overactive bladder (OAB) symptoms after midurethral sling in female stress urinary incontinence (SUI) patients with or without neurological disease without spinal cord injury. Methods Patients who underwent midurethral sling for SUI between January 2009 and December 2018 were reviewed. Postoperative changes in OAB symptoms (de novo occurrence or resolution) within one year were compared in each preoperative symptom subset with a 1:1 matched analysis between non-neurological disease (NND) and neurological disease (ND) group. Results A total of 855 patients (median follow-up: 49.8 months; mean age: 57.9 ± 9.3 years) were included. Successful SUI correction was achieved in 95.0% of NND and 93.7% of ND patients (p=0.440). Among 797 patients (711 NND and 86 ND) without remnant SUI, 227 had SUI only, 198 had SUI with urgency, and 372 had mixed urinary incontinence (MUI) preoperatively. The ND patients tended to be older (62.8 ± 9.2 years vs. 57.2 ± 9.0 years) and had higher proportions of diabetes (24.4% vs. 8.0%), hypertension (47.7% vs. 26.7%), and MUI (64.0% vs. 44.6%) than NND patients (p<0.001 respectively). After matching age, diabetes and hypertension, the incidence of de novo OAB was higher in ND patients (SUI only; 21.1% vs. 5.3%, p<0.001) while resolution rates of urgency urinary incontinence (UUI) were similar (MUI; 57.7% vs. 53.9%, p=0.414). Conclusions Success rates of midurethral sling and resolution of UUI were comparable between NND and ND patients. In patients with neurological conditions, de novo OAB symptoms were more likely to develop. keywords : midurethral sling, neurologic disease