Basic Research - Infertility & Sexual Dysfunction(구연) (E-025) 감각유발전위와 근치적전립선절제술 후 발기장애의 관련성: 전향적 연구 동국대학교 의과대학 비뇨의학과교실 권세윤, 박동진, 서영진, 이경섭 Introduction and Objective: Somatosensory evoked potential (SSEP) has been studied in erectile dysfunctions (ED). We aimed to evaluate correlation with SSEP and ED in patients undergoing radical prostatectomy (RP). We used pudendal nerve SSEP. Materials and Methods: We prospectively analyzed data from 57 patients who underwent radical prostatectomy from January 2016 and December 2018, with at least 6 months of follow-up. Patients were divided into 2 groups depending on the presence/absence of erectile dysfunction. Demographic characteristics, preoperative evaluations, postoperative outcomes and pudendal nerve SSEP before and after RP were assessed. In pudendal nerve SSEP, stimulating electrodes are placed at penis, and recording electrodes are placed at levels of lumbar spine (L1) and cortex. Cortical and lumbar latencies were obtained with stimulation of the pudendal nerve using averaging technique. Erectile function recovery was defined as question 2 and 3 on the Ineternational Index of Erectile Function (IIEF)-5. Results: Patients with/without postoperative erectile dysfunction were 20 and 37, respectively. Demographic characteristics and perioperative outcomes according to presence/absence of erectile dysfunction were similar. Patients with erectile dysfunction showed significant increase in lumbar (16.0 vs 17.5 ms, p=0.034) and cortical (49.2 vs 53.0 ms, p=0.001) latencies of pudendal nerve SSEP after surgery. They also showed significant prolongation of lumbar (3.0 vs 5.1 ms, p=0.009) and cortical (2.3 vs 5.1 ms, p=0.001) latencies of pudendal nerve SSEP before and after RP. Conclusions: Our results suggest that pudendal nerve SSEP can be an effective tool in the evaluation of patients with erectile dysfunction. The test can be used to provide more definitive assessment of erectile dysfunction. keywords : evoked potentials, somatosensory, erectile function