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Relationship between chronic periodontitis and lower urinary tract symptoms/benign prostatic hyperplasia |
| 을지병원 , 국립경찰병원¹ |
| 이준호, 박연원¹, 조인창¹, 김병훈¹, 최재덕, 조정만, 강정윤, 유탁근 |
<strong>Introduction</strong>: Chronic periodontitis is an infectious disease resulting in inflammation within the supporting tissue of the teeth, progressive attachment, and bone loss. Recent data showed that chronic periodontitis was related to systemic diseases. This study was conducted to investigate the relationship between chronic periodontitis and LUTS/BPH.
<strong>Methods</strong>:
A total of 208 men in their 40s and 50s who had received a health checkup were included. All of the data from the participants were collected prospectively. Chronic periodontitis was defined as a 30 % increase in clinical attachment level (CAL)≥4mm of the total probed site. And, CAL was defined as the distance between the cementoenamel junction of the tooth and the deepest aspect of the pocket. All periodontal examinations were performed by a single periodontist who was blind urological data. LUTS/BPH was assessed using IPSS, transrectal ultrasonography, uroflowmetry, and postvoiding residual urine volume. Additionally, a full metabolic workup including testosterone was carried out.
<strong>Results</strong>:
Median age, total prostate volume, IPSS total score, average flow rate, and maximal flow rate were 55.0 years old, 29.0 mL, 9.0, 9.0 mL/sec, and 20.5 mL/sec, respectively. In addition, the prevalence of chronic periodontitis was 26.7%. IPSS total, IPSS voiding, IPSS storage, and QoL score were significantly higher in patients with chronic periodontitis (median [interquartile range], P; IPSS total, 8.0 [5.0-13.5] vs. 12.0 [7.5-20.5], P=.004; IPSS voiding, 5.0 [2.0-9.0] vs. 8.5 [4.0-15.0], P=.002; IPSS storage, 3.0 [2.0-5.0] vs. 4.0 [3.0-6.0], P=.021; QoL, 2.0 [1.0-3.0] vs. 3.0 [2.0-4.0], P=.015). And, average flow rate was significantly lower in patients with chronic periodontitis (median [interquartile range] (mL/sec), P; 9.0 [8.0-13.0] vs. 8.0 [6.0-11.0], P=.042). After adjusting for age, testosterone, prostate volume, glucose, total cholesterol, and waist circumference, IPSS total and IPSS voiding score were significantly and positively related to chronic periodontitis (Estimated, Std. Error, P; IPSS total, 4.9498, 1.8573, .0093; IPSS voiding, 4.0077, 1.2835, .0025).
<strong>Conclusions</strong>:
Our data suggest that LUTS/BPH is significantly related to chronic periodontitis. |
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keywords : Chronic periodontitis, Lower urinary tract symptoms, Benign prostatic hyperplasia |
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