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남성에게서 하부요로증상의 악화와 방광내 전립선 돌출과의 연관성 |
| 전남대학교 의과대학 비뇨의학과교실 |
| 구진석, 조현진, 송재익, 이호연, 김재현, 임도경, 김태희, 은성종, 오주용, 유성현, 김명수, 정호석, 황의창, 오경진, 김선옥, 정승일, 강택원, 권동득, 박광성 |
PURPOSE:
This study aimed to evaluate the association of intravesical prostatic protrusion (IPP) with lower urinary tract symptom (LUTS) in male patients.
METHODS:
This study was conducted on a total of 1303 men who visited our outpatient clinic due to lower urinary tract symptoms from January 2015 to December 2019. Age, comorbidities, prostate specific antigen (PSA), testosterone level, BPH-related parameters and uroflowmetric parameters were assessed. IPP was calculated in the mid-sagittal section of transrectal ultrasonography. According to the degree of IPP, patients was classified as 4 groups; none, grade 1 (≤ 5 mm), grade 2 (5-10 mm), and grade 3 (> 10 mm). We evaluated the relationship of IPP with multiple parameters of BPH/LUTS.
RESULTS:
The mean age of the patients was 68.0 ± 8.2 years. Mean IPPs were 3.7 ± 0.8 mm (grade 1, n = 288), 7.4 ± 1.4 mm (grade 2, n = 154), and 15.1 ± 4.4 mm (grade 3, n = 50), respectively. IPP was correlated with all subcategorized IPSS (total, voiding, storage, QoL, p<0.05) According to the severity of IPP, Grade 3 IPP group showed significantly worse IPPS score (total, voiding, storage, QoL, p<0.001) despite small prostate volume. The history of cerebrovascular disease and cardiovascular disease were significantly associated with IPP (p=0.011 and p=0.037, respectively) on multivariate analysis.
CONCLUSION:
In this study, IPP was significantly related with the storage, voiding symptoms of IPSS and quality of life. In addition, clinicians should be aware that severe IPP (> 10 mm) could independently associate with worse symptoms of LUTS in men. |
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keywords : Intravesical prostatic protrusion, Lower urinary tract symptom, Benign prostatic hyperplasia |
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