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남성의 하부요로증상의 평가에 있어서 요도 주위 석회화의 역할 |
| 전남대학교 의과대학 비뇨의학과교실 |
| 구진석, 조현진, 송재익, 이호연, 김재현, 임도경, 김태희, 은성종, 오주용, 유성현, 김명수, 정호석, 황의창, 오경진, 김선옥, 정승일, 강택원, 권동득, 박광성 |
Objectives
We aimed to evaluate the association of periurethral calcification (PUC) with uroflowmetry and symptom severity in male patients with lower urinary tract symptoms (LUTS).
Methods
The data was collected from 1321 men with lower urinary tract symptoms who visited our hospital from January 2015 to December 2019. The severity and location of PUC was evaluated on the midsagittal plane of a trans-rectal ultrasonography. The relationships between age, prostate-related parameters, International Prostate Symptom Score (IPSS), and uroflowmetric parameters were assessed.
Results
Among total 1321, 530 (40.1%) had periurethral calcification; 310 (23.5%) with mild PUC, 142 (10.8%) with moderate PUC, and 78 (5.9%) with severe PUC, respectively. The PUC-group had significantly severe prostate symptom score (15.1 ± 8.7 vs 13.1 ± 7.9, p<0.001) and low peak flow rate (Qmax, mL/s) (12.4 ± 6.6 vs 14.7 ± 13.3, p<0.001) compared to non-PUC group. According to the severity of PUC, there was a tendency that patients in severe PUC groups showed high PSA (p=0.009) and total IPSS (p<0.001), and low Qmax (p=0.002) despite small prostate volume (p<0.001). In multivariate analysis, distal-PUC was independently associated with total IPSS (p=0.02), voiding symptom score (p=0.04), storage symptom score (p=0.023) and Qmax (p=0.015).
Conclusion
In this study, PUC was significantly related with the LUTS parameters in terms of IPSS and Qmax. In addition, distal location of PUC could independently associate with worse symptoms of LUTS-BPH in men. |
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keywords : Periurethral calcification, Benign prostatic hyperplasia, Lower urinary tract symptom |
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