Cancer - Prostate(구연) (E-108) MRI/TRUS 소프트웨어 융합 전립선조직검사에서 PI-RADS version 2에 따른 peripheral zone과 transitional zone 병변의 전립선암 진단률 비교 양산부산대학교병원 비뇨의학과 송원훈, 이단비, 백승룡, 이승수, 남종길, 박성우 Objectives: In PI-RADS version 2 using mpMRI, the scoring system for peripheral zone and transitional zone lesions is different. The prostate cancer diagnosis rate of peripheral and transitional zone lesions according to PI-RADS version 2 in MRI/TRUS software fusion prostate biopsy was compared. Materials and Methods: From October 2019 to May 2020, a total of 126 patients who underwent mpMRI and who underwent MRI/TRUS software fusion prostate biopsy were analyzed retrospectively. The diagnostic rates of the overall prostate cancer and clinically significant prostate cancer (csPCa) of the two groups of peripheral (PZ) and transitional zone lesions (TZ) according to the Prostate Image Reporting and Data System (PI-RADS) version 2 were compared. Results: The number of patients, region of interest (ROI), PSA of the PZ and TZ were 56, 70, 6.3 (0.8-269.0), and 70, 96, 7.1 (0.008-121.0), respectively. The number of PI-RADS 3, 4, 5 of the PZ and TZ were 34 (48.6%), 31 (44.3%), 4 (5.7%), and 36 (37.5), 47 (49.0), 12 (12.5), respectively. The csPCa diagnosis rates for PI-RADS 3, 4, 5 of the PZ and TZ in overall lesion were 5.9% and 2.8% (P=0.522), 51.6% and 23.4% (P=0.028), 75.0% and 41.7% (P=0.319), respectively. The csPCa diagnosis rates in target lesions for PI-RADS 3, 4, 5 of the PZ and TZ were 5.9% and 0.0% (P=0.140), 45.2% and 10.6% (P=0.002), 75.0% and 14.7% (P=0.319), respectively. Conclusion: The diagnosis rate in the PZ was significantly higher than that of the TZ in PI-RADS version 2. It may be necessary to improve the interpretation of PI-RADS for the transitional zone. keywords : prostate cancer, PI-RADS version 2, peripheral and transitional zone