Cancer - Bladder, Pelvis, Ureter & Others(구연) (E-061) 로봇 근치적 방광 절제술과 개복 근치적 방광 절제술의 삶의 질에 대한 연구 - EQ-5D-5L 설문지를 통한 분석 서울대학교 의과대학 비뇨의학교실 유상현, 윤현식, 정규환, 박대형, 이수빈, 서준교, 육형동, 정창욱, 김현회, 곽철, 구자현 Objective The concept of the quality of life has been consistently important in many diseases, and is also important in urological diseases. The objective of the current study was to compare the quality of life between robot assisted radical cystectomy (RARC) and open radical cystectomy (ORC) by analyzing the EQ-5D-5L questionnaire. Materials & Methods We analyzed 249 patients from the Seoul National University Prospectively Enrolled Registry for Urothelial Cancer – Radical Cystectomy (SUPER-UC-Cx), enrolled from March 2016 to September 2019. After excluding cases of partial cystectomy and foreign patients, 244 patients remained in the final study cohort. The whole group was divided into RARC group (n=56), and ORC group (n=188). We followed up until one year after surgery and analyzed the questionnaire collected from patients in the outpatient clinic before surgery, 1 month, 3 months, 6 months, and 12 months after surgery. We converted the score of the EQ-5D-5L questionnaire to Korean validation version. We obtained a healthy utility score by calculating the average value of the overall scores. Results 244 patients were included in this study, and the response rate of questionnaire was 219 (89.4%, pre-operation), 131 (53.5%, 1 month), 172 (70.2%, 3 months), 159 (64.9%, 6 months), 118 (48.2%, 12 months) in each period. We found no significant differences in the self-measurement health status score in such period; pre-operation, RARC vs. ORC, 0.846±0.123 vs. 0.813±0.175, p=0.220; post-operation 1 month, 0.733±0.164 vs. 0.761±0.176, p=0.441; 3 months, 0.800±0.166 vs. 0.756±0.205, p=0.211; 6 months, 0.850±0.123 vs. 0.803±0.186, p=0.165. The RARC group had higher score than the ORC group in only post-op 12 months (0.858±0.157 vs. 0.762±0.215, p=0.017). However, there were no significant differences in healthy utility score between two groups (0.796±0.157 vs. 0.761±0.176, p=0.195) Conclusion There were not any significant differences of healthy utility score between robot assisted radical cystectomy and open radical cystectomy. Our study can be helpful information about cost-effectiveness, and clinicians can utilize this to consult patients and set the treatment plan. keywords : Department of Urology, Seoul National University Hospital, Seoul, Korea