Cancer - Prostate(구연) (E-118) Comparison of biparametric MRI and multiparametric MRI in prostate cancer diagnosis: Is multiparametric MRI necessary for detection of clinically significant prostate cancer? 부산대학교 의과대학 비뇨기과학교실 박지훈, 강병진, 박시균, 이권경, 김경환, 구자윤, 하홍구 INTRODUCTION In PI-RADS, dynamic contrast enhancement (DCE) plays a role of distinguishing between PI-RADS 3 and 4 according to DCE in the DWI 3 lesion of the peripheral zone. It is argued that biparametric MRI(bpMRI) without the DCE protocol is sufficient to detect clinically significant prostate cancer(csPCa). MATERIALS AND METHODS Among patients diagnosed with PCa by performing MR-fusion prostate biopsy(PBx) after bpMRI at Pusan National University Hospital from July 2017 to February 2020, patients undergoing mpMRI and radical prostatectomy (RP) in the same hospital enrolled. The ISUP group of PBx and RP and the PI-RADS score of bpMRI and mpMRI were compared and evaluated. Gleason score (GS) 7 or higher was defined as csPCa. RESULTS The average age of 106 enrolled children was 65.83 (95% CI 64.753-66.907), and the average PSA was 10.5047 (95% CI 8.124-12.885). When evaluating changes in PI-RADS scores of bpMRI and mpMRI in the ISUP group diagnosed with PBx and RP, it was found that the PI-RADS score changes less as the ISUP group increases(Table 1). It showed that there was a significant relationship with the consistency of PI-RADS score in csPCa compared to GS6 PCa(table 2). CONCLUSION As for csPCa, the difference in PI-RADS score between bpMRI and mpMRI is insignificant, so it can be considered that bpMRI is sufficient to diagnose csPCa. keywords : biparametric MRI, clinically significant prostate cancer, PI-RADS