Cancer - Bladder, Pelvis, Ureter & Others(구연) (E-060) Prognostic significance of preoperative controlling nutritional status (CONUT) score for recurrence after trans-urethral resection of bladder tumor in non-muscle invasive bladder cancer Urology, Seoul National University Hospital, Urology, Seoul National University Hospital, Urology, Seoul National University Hospital, Urology, Seoul National University Hospital, Urology, Seoul National University Hospital, Urology, Seoul National University Hospital, Urology, Seoul National University Hospital, Urology, Seoul National University Hospital, Urology, Seoul National University Hospital, Urology, Seoul National University Hospital Jee Hwan Yun, Jungyo Suh, Sang Hyun Yoo, Hyun Sik Yoon, Dae Hyung Park, Gyu Hwan Jung, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, Ja Hyun Ku Background: The controlling nutritional status (CONUT) score represents the nutritional status of the individuals. The prognostic impact of preoperative controlling nutritional status (CONUT) score has been reported in many malignancies in decades. Until now, the clinical importance of preoperative CONUT scores in bladder cancer ontological outcomes is not well researched.  / Objectives: This study aims to discover the clinical impact CONUT score for recurrence after trans-urethral resection of bladder tumor (TURBT) in non-muscle invasive bladder cancer (NMIBC).  / Materials and Methods: We used patient data collected from the prospective cohort; Seoul National University Prospectively Enrolled Registry for Urothelial cancer TURBT (SUPER-UC-TURBT). From pre-operative laboratory test, we calculated CONUT score by the combination of serum albumin, total lymphocyte count, and total cholesterol level. We defined a CONUT score of 0–1 as normal and over 2 as high. Kaplan-Meier curve with the log-rank test was compared between normal and high CONUT score groups for recurrence-free survival and progression-free survival.   / Results and Conclusion: All 712 NMIBC patients who underwent TURBT from Mar 2016 to April 2020 enrolled for this analysis. The average age was 70.0 ± 12.0 and 149 patient (20.9%) was female. The average follow-up period was 30.9 ± 9.7 months. Most of the patient case was initial TURBT and only 48 patients (6.7%) has previous TURBT history. From Kaplan-Meiyer analysis, normal CONUT group statistically significant longer recurrence-free survival than high CONUT score group (37.4±0.8 months vs 29.0±1.8 months, p-value <0.001). However, progression-free survival was not different between the two groups (46.9±0.2 months vs. 46.4±0.7 months, p-value =0.43). We found the prognostic significance of preoperative CONUT score for recurrence after TURBT in NMIBC.  keywords : CONUT score, non-muscle invasive bladder cancer